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Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity

BACKGROUND: Lowering oxygen from atmospheric level (hyperoxia) to the physiological level (physioxia) of articular cartilage promotes mesenchymal stem cell (MSC) chondrogenesis. However, the literature is equivocal regarding the benefits of physioxic culture on preventing hypertrophy of MSC-derived...

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Detalles Bibliográficos
Autores principales: Anderson, Devon E., Markway, Brandon D., Bond, Derek, McCarthy, Helen E., Johnstone, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073443/
https://www.ncbi.nlm.nih.gov/pubmed/27765063
http://dx.doi.org/10.1186/s13287-016-0419-8