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Activation of HIV-1 expression in latently infected CD4+ T cells by the small molecule PKC412

BACKGROUND: HIV-1 latency is a major obstacle for HIV-1 eradication. Extensive efforts are being directed toward the reactivation of latent HIV reservoirs with the aim of eliminating latently infected cells via the host immune system and/or virus-mediated cell lysis. RESULTS: We screened over 1,500...

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Detalles Bibliográficos
Autores principales: Ao, Zhujun, Zhu, Rong, Tan, Xiaoli, Liu, Lisa, Chen, Liyu, Liu, Shuiping, Yao, XiaoJian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073835/
https://www.ncbi.nlm.nih.gov/pubmed/27769267
http://dx.doi.org/10.1186/s12985-016-0637-9