Cargando…
Activation of HIV-1 expression in latently infected CD4+ T cells by the small molecule PKC412
BACKGROUND: HIV-1 latency is a major obstacle for HIV-1 eradication. Extensive efforts are being directed toward the reactivation of latent HIV reservoirs with the aim of eliminating latently infected cells via the host immune system and/or virus-mediated cell lysis. RESULTS: We screened over 1,500...
Autores principales: | Ao, Zhujun, Zhu, Rong, Tan, Xiaoli, Liu, Lisa, Chen, Liyu, Liu, Shuiping, Yao, XiaoJian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073835/ https://www.ncbi.nlm.nih.gov/pubmed/27769267 http://dx.doi.org/10.1186/s12985-016-0637-9 |
Ejemplares similares
-
Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells
por: Li, Jian-Ping, et al.
Publicado: (2016) -
R88-APOBEC3Gm Inhibits the Replication of Both Drug-resistant Strains of HIV-1 and Viruses Produced From Latently Infected Cells
por: Wang, Xiaoxia, et al.
Publicado: (2014) -
Inactivation of microbial infectiousness by silver nanoparticles-coated condom: a new approach to inhibit HIV- and HSV-transmitted infection
por: Mohammed Fayaz, A, et al.
Publicado: (2012) -
Search for small molecule activators of latent HIV
por: Geleziunas, Romas, et al.
Publicado: (2012) -
Current Advances in Virus-Like Particles as a Vaccination Approach against HIV Infection
por: Zhao, Chongbo, et al.
Publicado: (2016)