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Exceptionally long-range haplotypes in Plasmodium falciparum chromosome 6 maintained in an endemic African population

BACKGROUND: Previous genome-wide analyses of single nucleotide variation in Plasmodium falciparum identified evidence of an extended haplotype region on chromosome 6 in West Africa, suggesting recent positive selection. Such a pattern is not seen in samples from East Africa or South East Asia, so it...

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Detalles Bibliográficos
Autores principales: Amambua-Ngwa, Alfred, Danso, Bakary, Worwui, Archibald, Ceesay, Sukai, Davies, Nwakanma, Jeffries, David, D’Alessandro, Umberto, Conway, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073846/
https://www.ncbi.nlm.nih.gov/pubmed/27769292
http://dx.doi.org/10.1186/s12936-016-1560-7