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Incorporating topological information for predicting robust cancer subnetwork markers in human protein-protein interaction network
BACKGROUND: Discovering robust markers for cancer prognosis based on gene expression data is an important yet challenging problem in translational bioinformatics. By integrating additional information in biological pathways or a protein-protein interaction (PPI) network, we can find better biomarker...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073942/ https://www.ncbi.nlm.nih.gov/pubmed/27766944 http://dx.doi.org/10.1186/s12859-016-1224-1 |