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Effective comparative analysis of protein-protein interaction networks by measuring the steady-state network flow using a Markov model

BACKGROUND: Comparative analysis of protein-protein interaction (PPI) networks provides an effective means of detecting conserved functional network modules across different species. Such modules typically consist of orthologous proteins with conserved interactions, which can be exploited to computa...

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Detalles Bibliográficos
Autores principales: Jeong, Hyundoo, Qian, Xiaoning, Yoon, Byung-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073945/
https://www.ncbi.nlm.nih.gov/pubmed/27766938
http://dx.doi.org/10.1186/s12859-016-1215-2