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Effective comparative analysis of protein-protein interaction networks by measuring the steady-state network flow using a Markov model
BACKGROUND: Comparative analysis of protein-protein interaction (PPI) networks provides an effective means of detecting conserved functional network modules across different species. Such modules typically consist of orthologous proteins with conserved interactions, which can be exploited to computa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073945/ https://www.ncbi.nlm.nih.gov/pubmed/27766938 http://dx.doi.org/10.1186/s12859-016-1215-2 |