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VDJML: a file format with tools for capturing the results of inferring immune receptor rearrangements

BACKGROUND: The genes that produce antibodies and the immune receptors expressed on lymphocytes are not germline encoded; rather, they are somatically generated in each developing lymphocyte by a process called V(D)J recombination, which assembles specific, independent gene segments into mature comp...

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Detalles Bibliográficos
Autores principales: Toby, Inimary T., Levin, Mikhail K., Salinas, Edward A., Christley, Scott, Bhattacharya, Sanchita, Breden, Felix, Buntzman, Adam, Corrie, Brian, Fonner, John, Gupta, Namita T., Hershberg, Uri, Marthandan, Nishanth, Rosenfeld, Aaron, Rounds, William, Rubelt, Florian, Scarborough, Walter, Scott, Jamie K., Uduman, Mohamed, Vander Heiden, Jason A., Scheuermann, Richard H., Monson, Nancy, Kleinstein, Steven H., Cowell, Lindsay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073965/
https://www.ncbi.nlm.nih.gov/pubmed/27766961
http://dx.doi.org/10.1186/s12859-016-1214-3