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VDJML: a file format with tools for capturing the results of inferring immune receptor rearrangements
BACKGROUND: The genes that produce antibodies and the immune receptors expressed on lymphocytes are not germline encoded; rather, they are somatically generated in each developing lymphocyte by a process called V(D)J recombination, which assembles specific, independent gene segments into mature comp...
Autores principales: | Toby, Inimary T., Levin, Mikhail K., Salinas, Edward A., Christley, Scott, Bhattacharya, Sanchita, Breden, Felix, Buntzman, Adam, Corrie, Brian, Fonner, John, Gupta, Namita T., Hershberg, Uri, Marthandan, Nishanth, Rosenfeld, Aaron, Rounds, William, Rubelt, Florian, Scarborough, Walter, Scott, Jamie K., Uduman, Mohamed, Vander Heiden, Jason A., Scheuermann, Richard H., Monson, Nancy, Kleinstein, Steven H., Cowell, Lindsay G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073965/ https://www.ncbi.nlm.nih.gov/pubmed/27766961 http://dx.doi.org/10.1186/s12859-016-1214-3 |
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