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Hypomethylation of Interleukin-6 Promoter is Associated with the Risk of Coronary Heart Disease

BACKGROUND: Interleukin-6 (IL-6) is implicated in the pathogenesis of coronary heart disease (CHD), and IL-6 expression has associated with reduced DNA methylation of its gene promoter. However, there are no data on IL-6 promoter methylation and the risk of CHD. OBJECTIVE: To examine whether IL-6 pr...

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Detalles Bibliográficos
Autores principales: Zuo, Hong-Peng, Guo, Ying-Yu, Che, Lin, Wu, Xian-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074066/
https://www.ncbi.nlm.nih.gov/pubmed/27627640
http://dx.doi.org/10.5935/abc.20160124