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Tissue distribution of teneligliptin in rats and comparisons with data reported for other dipeptidyl peptidase‐4 inhibitors

The tissue distribution of teneligliptin, a dipeptidyl peptidase (DPP)‐4 inhibitor, was investigated in rats, and compared with tissue distributions previously reported for other DPP‐4 inhibitors. Following the oral administration of [(14)C]teneligliptin to Sprague–Dawley rats, it was predominantly...

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Detalles Bibliográficos
Autores principales: Nakamaru, Yoshinobu, Akahoshi, Fumihiko, Iijima, Hiroaki, Hisanaga, Noriko, Kume, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074247/
https://www.ncbi.nlm.nih.gov/pubmed/26749565
http://dx.doi.org/10.1002/bdd.2003