Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium – application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data

Intra‐tumor heterogeneity is a vivid problem of molecular oncology that could be addressed by imaging mass spectrometry. Here we aimed to assess molecular heterogeneity of oral squamous cell carcinoma and to detect signatures discriminating normal and cancerous epithelium. Tryptic peptides were anal...

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Detalles Bibliográficos
Autores principales: Widlak, Piotr, Mrukwa, Grzegorz, Kalinowska, Magdalena, Pietrowska, Monika, Chekan, Mykola, Wierzgon, Janusz, Gawin, Marta, Drazek, Grzegorz, Polanska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074322/
https://www.ncbi.nlm.nih.gov/pubmed/27168173
http://dx.doi.org/10.1002/pmic.201500458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074322/
https://www.ncbi.nlm.nih.gov/pubmed/27168173
http://dx.doi.org/10.1002/pmic.201500458

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