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Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium – application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data
Intra‐tumor heterogeneity is a vivid problem of molecular oncology that could be addressed by imaging mass spectrometry. Here we aimed to assess molecular heterogeneity of oral squamous cell carcinoma and to detect signatures discriminating normal and cancerous epithelium. Tryptic peptides were anal...
Autores principales: | Widlak, Piotr, Mrukwa, Grzegorz, Kalinowska, Magdalena, Pietrowska, Monika, Chekan, Mykola, Wierzgon, Janusz, Gawin, Marta, Drazek, Grzegorz, Polanska, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074322/ https://www.ncbi.nlm.nih.gov/pubmed/27168173 http://dx.doi.org/10.1002/pmic.201500458 |
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