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Silencing of ASC in Cutaneous Squamous Cell Carcinoma

Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is an important adaptor protein for inflammasome activation, mediating the secretion of protumorigenic innate cytokines. However, ASC is also known to trigger apoptosis in tumor cells, acting as a tumor-suppressor...

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Detalles Bibliográficos
Autores principales: Meier, Katharina, Drexler, Stefan K., Eberle, Franziska C., Lefort, Karine, Yazdi, Amir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074456/
https://www.ncbi.nlm.nih.gov/pubmed/27768771
http://dx.doi.org/10.1371/journal.pone.0164742