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Inhibition of an Erythrocyte Tyrosine Kinase with Imatinib Prevents Plasmodium falciparum Egress and Terminates Parasitemia

With half of the world’s population at risk for malaria infection and with drug resistance on the rise, the search for mutation-resistant therapies has intensified. We report here a therapy for Plasmodium falciparum malaria that acts by inhibiting the phosphorylation of erythrocyte membrane band 3 b...

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Detalles Bibliográficos
Autores principales: Kesely, Kristina R., Pantaleo, Antonella, Turrini, Francesco M., Olupot-Olupot, Peter, Low, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074466/
https://www.ncbi.nlm.nih.gov/pubmed/27768734
http://dx.doi.org/10.1371/journal.pone.0164895