Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease

Flavin-containing monooxygenase 3 (FMO3) is known primarily as an enzyme involved in the metabolism of therapeutic drugs. On a daily basis, however, we are exposed to one of the most abundant substrates of the enzyme trimethylamine (TMA), which is released from various dietary components by the acti...

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Detalles Bibliográficos
Autores principales: Fennema, Diede, Phillips, Ian R., Shephard, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074467/
https://www.ncbi.nlm.nih.gov/pubmed/27190056
http://dx.doi.org/10.1124/dmd.116.070615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074467/
https://www.ncbi.nlm.nih.gov/pubmed/27190056
http://dx.doi.org/10.1124/dmd.116.070615

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