MUC1-ARF—A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA

Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The MUC1 gene encodes MUC1-TM, a signal-transducing trans-membrane protein highly expressed in human malignancies. Here we show that an AUG codon do...

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Detalles Bibliográficos
Autores principales: Chalick, Michael, Jacobi, Oded, Pichinuk, Edward, Garbar, Christian, Bensussan, Armand, Meeker, Alan, Ziv, Ravit, Zehavi, Tania, Smorodinsky, Nechama I., Hilkens, John, Hanisch, Franz-Georg, Rubinstein, Daniel B., Wreschner, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074479/
https://www.ncbi.nlm.nih.gov/pubmed/27768738
http://dx.doi.org/10.1371/journal.pone.0165031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074479/
https://www.ncbi.nlm.nih.gov/pubmed/27768738
http://dx.doi.org/10.1371/journal.pone.0165031

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