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The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling

Pressure overload is a frequent cause of heart failure. Heart failure affects millions of patients worldwide and is a major cause of morbidity and mortality. Cell surface proteoglycans are emerging as molecular players in cardiac remodeling, and increased knowledge about their regulation and functio...

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Detalles Bibliográficos
Autores principales: Melleby, Arne O., Strand, Mari E., Romaine, Andreas, Herum, Kate M., Skrbic, Biljana, Dahl, Christen P., Sjaastad, Ivar, Fiane, Arnt E., Filmus, Jorge, Christensen, Geir, Lunde, Ida G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074531/
https://www.ncbi.nlm.nih.gov/pubmed/27768722
http://dx.doi.org/10.1371/journal.pone.0165079