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The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
Pressure overload is a frequent cause of heart failure. Heart failure affects millions of patients worldwide and is a major cause of morbidity and mortality. Cell surface proteoglycans are emerging as molecular players in cardiac remodeling, and increased knowledge about their regulation and functio...
Autores principales: | Melleby, Arne O., Strand, Mari E., Romaine, Andreas, Herum, Kate M., Skrbic, Biljana, Dahl, Christen P., Sjaastad, Ivar, Fiane, Arnt E., Filmus, Jorge, Christensen, Geir, Lunde, Ida G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074531/ https://www.ncbi.nlm.nih.gov/pubmed/27768722 http://dx.doi.org/10.1371/journal.pone.0165079 |
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