Structures of NS5 Methyltransferase from Zika Virus

The Zika virus (ZIKV) poses a major public health emergency. To aid in the development of antivirals, we present two high-resolution crystal structures of the ZIKV NS5 methyltransferase: one bound to S-adenosylmethionine (SAM) and the other bound to SAM and 7-methyl guanosine diphosphate (7-MeGpp)....

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Detalles Bibliográficos
Autores principales: Coloma, Javier, Jain, Rinku, Rajashankar, Kanagalaghatta R., García-Sastre, Adolfo, Aggarwal, Aneel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074680/
https://www.ncbi.nlm.nih.gov/pubmed/27633330
http://dx.doi.org/10.1016/j.celrep.2016.08.091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074680/
https://www.ncbi.nlm.nih.gov/pubmed/27633330
http://dx.doi.org/10.1016/j.celrep.2016.08.091

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