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Local analgesic effect of tramadol is mediated by opioid receptors in late postoperative pain after plantar incision in rats

Tramadol is a drug used to treat moderate to severe pain. It is known to present a peripheral effect, but the local mechanisms underlying its actions remain unclear. The role of peripheral opioid receptors in postoperative pain is not well understood. In the present study, we examined the peripheral...

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Detalles Bibliográficos
Autores principales: de Oliveira Junior, José Oswaldo, de Freitas, Milena Fernandes, Bullara de Andrade, Carolina, Chacur, Marucia, Ashmawi, Hazem Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074711/
https://www.ncbi.nlm.nih.gov/pubmed/27799813
http://dx.doi.org/10.2147/JPR.S117674