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Cancer: fundamentals behind pH targeting and the double-edged approach
The highly regulated pH of cells and the less-regulated pH of the surrounding extracellular matrix (ECM) is the result of a delicate balance between metabolic processes and proton production, proton transportation, chemical buffering, and vascular removal of waste products. Malignant cells show a pr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074768/ https://www.ncbi.nlm.nih.gov/pubmed/27799782 http://dx.doi.org/10.2147/OTT.S115438 |