Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells

[Image: see text] Protein prenylation is a post-translational modification that is responsible for membrane association and protein–protein interactions. The oncogenic protein Ras, which is prenylated, has been the subject of intense study in the past 20 years as a therapeutic target. Several studie...

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Detalles Bibliográficos
Autores principales: Palsuledesai, Charuta C., Ochocki, Joshua D., Kuhns, Michelle M., Wang, Yen-Chih, Warmka, Janel K., Chernick, Dustin S., Wattenberg, Elizabeth V., Li, Ling, Arriaga, Edgar A., Distefano, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074897/
https://www.ncbi.nlm.nih.gov/pubmed/27525511
http://dx.doi.org/10.1021/acschembio.6b00421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074897/
https://www.ncbi.nlm.nih.gov/pubmed/27525511
http://dx.doi.org/10.1021/acschembio.6b00421

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