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Therapeutic effects of histone deacetylase inhibitors in a murine asthma model

OBJECTIVE AND DESIGN: To investigate the therapeutic effects of various HDAC inhibitors on the development of chronic allergic airway disease in mice with airway inflammation, airway remodeling, and airway hyperresponsiveness. SUBJECTS: Wild-type BALB/C mice (N = 72). TREATMENT: Tubastatin A HCl [TS...

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Detalles Bibliográficos
Autores principales: Ren, Yuan, Su, Xinming, Kong, Lingfei, Li, Menglu, Zhao, Xuan, Yu, Na, Kang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075027/
https://www.ncbi.nlm.nih.gov/pubmed/27565183
http://dx.doi.org/10.1007/s00011-016-0984-4