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Pulmonary Deposition and Elimination of Liposomal Amikacin for Inhalation and Effect on Macrophage Function after Administration in Rats

Pulmonary nontuberculous mycobacterial (PNTM) infections represent a treatment challenge. Liposomal amikacin for inhalation (LAI) is a novel formulation currently in development for the treatment of PNTM infections. The pulmonary deposition and elimination of LAI and its effect on macrophage functio...

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Detalles Bibliográficos
Autores principales: Malinin, Vladimir, Neville, Mary, Eagle, Gina, Gupta, Renu, Perkins, Walter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075057/
https://www.ncbi.nlm.nih.gov/pubmed/27550345
http://dx.doi.org/10.1128/AAC.00700-16