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Development of a Novel Collagen Wound Model To Simulate the Activity and Distribution of Antimicrobials in Soft Tissue during Diabetic Foot Infection

Diabetes has major implications for public health, with diabetic foot ulcers (DFUs) being responsible for significant morbidity and mortality. A key factor in the development of nonhealing ulcers is infection, which often leads to the development of biofilm, gangrene, and amputation. A novel approac...

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Detalles Bibliográficos
Autores principales: Price, Bianca L., Lovering, Andrew M., Bowling, Frank L., Dobson, Curtis B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075099/
https://www.ncbi.nlm.nih.gov/pubmed/27620475
http://dx.doi.org/10.1128/AAC.01064-16