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N-methyl-D-aspartate receptor activation mediates lung fibroblast proliferation and differentiation in hyperoxia-induced chronic lung disease in newborn rats

BACKGROUND: Previous studies have suggested that endogenous glutamate and its N-methyl-D-aspartate receptors (NMDARs) play important roles in hyperoxia-induced acute lung injury in newborn rats. We hypothesized that NMDAR activation also participates in the development of chronic lung injury after w...

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Detalles Bibliográficos
Autores principales: Wang, YanRui, Yue, ShaoJie, Luo, ZiQiang, Cao, ChuanDing, Yu, XiaoHe, Liao, ZhengChang, Wang, MingJie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075180/
https://www.ncbi.nlm.nih.gov/pubmed/27769245
http://dx.doi.org/10.1186/s12931-016-0453-1