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Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells

BACKGROUND: High-grade non-muscle invasive bladder cancer (NMIBC) has a high risk of recurrence and progression to muscle-invasive forms, which seems to be largely related to the presence of tumorigenic stem-like cell populations that are refractory to conventional therapies. Here, we evaluated the...

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Detalles Bibliográficos
Autores principales: Ferreira-Teixeira, Margarida, Paiva-Oliveira, Daniela, Parada, Belmiro, Alves, Vera, Sousa, Vitor, Chijioke, Obinna, Münz, Christian, Reis, Flávio, Rodrigues-Santos, Paulo, Gomes, Célia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075212/
https://www.ncbi.nlm.nih.gov/pubmed/27769244
http://dx.doi.org/10.1186/s12916-016-0715-2