Oral administration of a non-absorbable plant cell-expressed recombinant anti-TNF fusion protein induces immunomodulatory effects and alleviates nonalcoholic steatohepatitis

AIM: To evaluate the immunomodulatory effect of oral administration of PRX-106 in the high-fat diet model. METHODS: For 22 wk, C57BL/6 HFD-fed mice received daily oral treatments with BY-2 cells expressing recombinant anti-tumor necrosis factor alpha fusion protein (PRX-106). Mice were followed for...

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Detalles Bibliográficos
Autores principales: Ilan, Yaron, Ben Ya'acov, Ami, Shabbat, Yehudit, Gingis-Velitski, Svetlana, Almon, Einat, Shaaltiel, Yoseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075550/
https://www.ncbi.nlm.nih.gov/pubmed/27818591
http://dx.doi.org/10.3748/wjg.v22.i39.8760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075550/
https://www.ncbi.nlm.nih.gov/pubmed/27818591
http://dx.doi.org/10.3748/wjg.v22.i39.8760

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