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Plasmid-Based Generation of Induced Neural Stem Cells from Adult Human Fibroblasts

Direct reprogramming from somatic to neural cell types has become an alternative to induced pluripotent stem cells. Most protocols employ viral expression systems, posing the risk of random genomic integration. Recent developments led to plasmid-based protocols, lowering this risk. However, these pr...

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Detalles Bibliográficos
Autores principales: Capetian, Philipp, Azmitia, Luis, Pauly, Martje G., Krajka, Victor, Stengel, Felix, Bernhardi, Eva-Maria, Klett, Mariana, Meier, Britta, Seibler, Philip, Stanslowsky, Nancy, Moser, Andreas, Knopp, Andreas, Gillessen-Kaesbach, Gabriele, Nikkhah, Guido, Wegner, Florian, Döbrössy, Máté, Klein, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075569/
https://www.ncbi.nlm.nih.gov/pubmed/27822179
http://dx.doi.org/10.3389/fncel.2016.00245