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Plasmid-Based Generation of Induced Neural Stem Cells from Adult Human Fibroblasts
Direct reprogramming from somatic to neural cell types has become an alternative to induced pluripotent stem cells. Most protocols employ viral expression systems, posing the risk of random genomic integration. Recent developments led to plasmid-based protocols, lowering this risk. However, these pr...
Autores principales: | Capetian, Philipp, Azmitia, Luis, Pauly, Martje G., Krajka, Victor, Stengel, Felix, Bernhardi, Eva-Maria, Klett, Mariana, Meier, Britta, Seibler, Philip, Stanslowsky, Nancy, Moser, Andreas, Knopp, Andreas, Gillessen-Kaesbach, Gabriele, Nikkhah, Guido, Wegner, Florian, Döbrössy, Máté, Klein, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075569/ https://www.ncbi.nlm.nih.gov/pubmed/27822179 http://dx.doi.org/10.3389/fncel.2016.00245 |
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