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Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats
Postoperative neurocognitive disorders are common complications in elderly patients following surgery or critical illness. High mobility group box 1 protein (HMGB1) is rapidly released after tissue trauma and critically involved in response to sterile injury. Herein, we assessed the role of HMGB1 af...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075578/ https://www.ncbi.nlm.nih.gov/pubmed/27822212 http://dx.doi.org/10.3389/fimmu.2016.00441 |