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Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats

Postoperative neurocognitive disorders are common complications in elderly patients following surgery or critical illness. High mobility group box 1 protein (HMGB1) is rapidly released after tissue trauma and critically involved in response to sterile injury. Herein, we assessed the role of HMGB1 af...

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Detalles Bibliográficos
Autores principales:	Terrando, Niccolò, Yang, Ting, Wang, Xueqin, Fang, Jiakai, Cao, Mengya, Andersson, Ulf, Erlandsson, Harris Helena, Ouyang, Wen, Tong, Jianbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075578/ https://www.ncbi.nlm.nih.gov/pubmed/27822212 http://dx.doi.org/10.3389/fimmu.2016.00441

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