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Exogenous Angiotensin I Metabolism in Aorta Isolated from Streptozotocin Treated Diabetic Rats

Purpose. Products of angiotensin (ANG) I metabolism may predispose to vascular complications of diabetes mellitus. Methods. Diabetes was induced with streptozotocin (75 mg/kg i.p.). Rat aorta fragments, isolated 4 weeks later, were pretreated with perindoprilat (3 μM), thiorphan (3 μM), or vehicle a...

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Detalles Bibliográficos
Autores principales: Wołkow, P. P., Bujak-Giżycka, B., Jawień, J., Olszanecki, R., Madej, J., Rutowski, J., Korbut, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075625/
https://www.ncbi.nlm.nih.gov/pubmed/27803936
http://dx.doi.org/10.1155/2016/4846819