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Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy

Human amniotic-fluid-derived mesenchymal stem cells (AF-MSCs) are interesting for their multilineage differentiation potential and wide range of therapeutic applications due to the ease of culture expansion. However, MSCs undergo replicative senescence. So far, the molecular mechanisms that underlie...

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Detalles Bibliográficos
Autores principales: Savickienė, Jūratė, Baronaitė, Sandra, Zentelytė, Aistė, Treigytė, Gražina, Navakauskienė, Rūta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075644/
https://www.ncbi.nlm.nih.gov/pubmed/27803714
http://dx.doi.org/10.1155/2016/2019498