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Two Case Reports of Rare BRAF Mutations in Exon 11 and Exon 15 with Discussion of Potential Treatment Options

BRAF mutations occur in up to 50% of melanomas. Mutations in the BRAF gene directly influence the patient's treatment because several inhibitors are available that only target BRAF(V600) mutations. Herein, we describe two cases of patients with metastatic melanomas, each carrying a ‘nonstandard...

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Detalles Bibliográficos
Autores principales: Richtig, Georg, Aigelsreiter, Ariane, Kashofer, Karl, Talakic, Emina, Kupsa, Romana, Schaider, Helmut, Richtig, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075727/
https://www.ncbi.nlm.nih.gov/pubmed/27790118
http://dx.doi.org/10.1159/000449125