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Antiplasmodial Activity Is an Ancient and Conserved Feature of Tick Defensins

Ancestral sequence reconstruction has been widely used to test evolution-based hypotheses. The genome of the European tick vector, Ixodes ricinus, encodes for defensin peptides with diverse antimicrobial activities against distantly related pathogens. These pathogens include fungi, Gram-negative, an...

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Detalles Bibliográficos
Autores principales: Cabezas-Cruz, Alejandro, Tonk, Miray, Bouchut, Anne, Pierrot, Christine, Pierce, Raymond J., Kotsyfakis, Michalis, Rahnamaeian, Mohammad, Vilcinskas, Andreas, Khalife, Jamal, Valdés, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075766/
https://www.ncbi.nlm.nih.gov/pubmed/27822206
http://dx.doi.org/10.3389/fmicb.2016.01682