Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies

New techniques to detect and quantify antibodies to nucleic acids would provide a significant advance over current methods, which often lack specificity. We investigate the potential of novel antigens containing locked nucleic acids (LNAs) as targets for antibodies. Particularly, employing molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Samuelsen, Simone V., Solov’yov, Ilia A., Balboni, Imelda M., Mellins, Elizabeth, Nielsen, Christoffer Tandrup, Heegaard, Niels H. H., Astakhova, Kira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075775/
https://www.ncbi.nlm.nih.gov/pubmed/27775006
http://dx.doi.org/10.1038/srep35827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075775/
https://www.ncbi.nlm.nih.gov/pubmed/27775006
http://dx.doi.org/10.1038/srep35827

Ejemplares similares