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Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies
New techniques to detect and quantify antibodies to nucleic acids would provide a significant advance over current methods, which often lack specificity. We investigate the potential of novel antigens containing locked nucleic acids (LNAs) as targets for antibodies. Particularly, employing molecular...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075775/ https://www.ncbi.nlm.nih.gov/pubmed/27775006 http://dx.doi.org/10.1038/srep35827 |