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Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers

Strategies to identify tumors at highest risk for treatment failure are currently under investigation for patients with bladder cancer. We demonstrate that flow cytometric detection of poorly differentiated basal tumor cells (BTCs), as defined by the co-expression of CD90, CD44 and CD49f, directly f...

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Detalles Bibliográficos
Autores principales: Skowron, K. B., Pitroda, S. P., Namm, J. P., Balogun, O., Beckett, M. A., Zenner, M. L., Fayanju, O., Huang, X., Fernandez, C., Zheng, W., Qiao, G., Chin, R., Kron, S. J., Khodarev, N. N., Posner, M. C., Steinberg, G. D., Weichselbaum, R. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075783/
https://www.ncbi.nlm.nih.gov/pubmed/27775025
http://dx.doi.org/10.1038/srep35854