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Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

Docosahexaenoic acid (DHA, 22:6n-3) is an omega-3 fatty acid essential for proper brain development. N-docosahexaenoylethanolamine (synaptamide), an endogenous metabolite of DHA, potently promotes neurogenesis, neuritogenesis and synaptogenesis; however, the underlying molecular mechanism is not kno...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Won, Huang, Bill X., Kwon, HeungSun, Rashid, Md Abdur, Kharebava, Giorgi, Desai, Abhishek, Patnaik, Samarjit, Marugan, Juan, Kim, Hee-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075789/
https://www.ncbi.nlm.nih.gov/pubmed/27759003
http://dx.doi.org/10.1038/ncomms13123