Bacterial mimetics of endocrine secretory granules as immobilized in vivo depots for functional protein drugs

In the human endocrine system many protein hormones including urotensin, glucagon, obestatin, bombesin and secretin, among others, are supplied from amyloidal secretory granules. These granules form part of the so called functional amyloids, which within the whole aggregome appear to be more abundan...

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Detalles Bibliográficos
Autores principales: Céspedes, María Virtudes, Fernández, Yolanda, Unzueta, Ugutz, Mendoza, Rosa, Seras-Franzoso, Joaquin, Sánchez-Chardi, Alejando, Álamo, Patricia, Toledo-Rubio, Verónica, Ferrer-Miralles, Neus, Vázquez, Esther, Schwartz, Simó, Abasolo, Ibane, Corchero, José Luis, Mangues, Ramon, Villaverde, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075894/
https://www.ncbi.nlm.nih.gov/pubmed/27775083
http://dx.doi.org/10.1038/srep35765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075894/
https://www.ncbi.nlm.nih.gov/pubmed/27775083
http://dx.doi.org/10.1038/srep35765

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