Pre-amyloid oligomers budding:a metastatic mechanism of proteotoxicity

The pathological hallmark of misfolded protein diseases and aging is the accumulation of proteotoxic aggregates. However, the mechanisms of proteotoxicity and the dynamic changes in fiber formation and dissemination remain unclear, preventing a cure. Here we adopted a reductionist approach and used...

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Detalles Bibliográficos
Autores principales: Bernini, Fabrizio, Malferrari, Daniele, Pignataro, Marcello, Bortolotti, Carlo Augusto, Di Rocco, Giulia, Lancellotti, Lidia, Brigatti, Maria Franca, Kayed, Rakez, Borsari, Marco, del Monte, Federica, Castellini, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075897/
https://www.ncbi.nlm.nih.gov/pubmed/27775057
http://dx.doi.org/10.1038/srep35865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075897/
https://www.ncbi.nlm.nih.gov/pubmed/27775057
http://dx.doi.org/10.1038/srep35865

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