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RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways

Glucocorticoids are steroids that reduce inflammation and are used as immunosuppressive drugs for many diseases. They are also the mainstay for the treatment of minimal change nephropathy (MCN), which is characterised by an absence of inflammation. Their mechanisms of action remain elusive. Evidence...

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Detalles Bibliográficos
Autores principales: Jiang, Lulu, Hindmarch, Charles C. T., Rogers, Mark, Campbell, Colin, Waterfall, Christy, Coghill, Jane, Mathieson, Peter W., Welsh, Gavin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075905/
https://www.ncbi.nlm.nih.gov/pubmed/27774996
http://dx.doi.org/10.1038/srep35671