Cargando…
Knowledge-guided fuzzy logic modeling to infer cellular signaling networks from proteomic data
Modeling of signaling pathways is crucial for understanding and predicting cellular responses to drug treatments. However, canonical signaling pathways curated from literature are seldom context-specific and thus can hardly predict cell type-specific response to external perturbations; purely data-d...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075921/ https://www.ncbi.nlm.nih.gov/pubmed/27774993 http://dx.doi.org/10.1038/srep35652 |