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Absence of Protoheme IX Farnesyltransferase CtaB Causes Virulence Attenuation but Enhances Pigment Production and Persister Survival in MRSA

The membrane protein CtaB in S. aureus is a protoheme IX farnesyltransferase involved in the synthesis of the heme containing terminal oxidases of bacterial respiratory chain. In this study, to assess the role of CtaB in S. aureus virulence, pigment production, and persister formation, we constructe...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Han, Jian, Zhang, Jia, Chen, Jiazhen, Wu, Nan, Zhang, Wenhong, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076432/
https://www.ncbi.nlm.nih.gov/pubmed/27822202
http://dx.doi.org/10.3389/fmicb.2016.01625