Cargando…
Absence of Protoheme IX Farnesyltransferase CtaB Causes Virulence Attenuation but Enhances Pigment Production and Persister Survival in MRSA
The membrane protein CtaB in S. aureus is a protoheme IX farnesyltransferase involved in the synthesis of the heme containing terminal oxidases of bacterial respiratory chain. In this study, to assess the role of CtaB in S. aureus virulence, pigment production, and persister formation, we constructe...
Autores principales: | Xu, Tao, Han, Jian, Zhang, Jia, Chen, Jiazhen, Wu, Nan, Zhang, Wenhong, Zhang, Ying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076432/ https://www.ncbi.nlm.nih.gov/pubmed/27822202 http://dx.doi.org/10.3389/fmicb.2016.01625 |
Ejemplares similares
-
Cytolytic toxin production by Staphylococcus aureus is dependent upon the activity of the protoheme IX farnesyltransferase
por: Stevens, Emily, et al.
Publicado: (2017) -
What is the “modified” CTAB protocol? Characterizing modifications to the CTAB DNA extraction protocol
por: Schenk, John J., et al.
Publicado: (2023) -
The Aspergillus fumigatus farnesyltransferase β-subunit, RamA, mediates growth, virulence, and antifungal susceptibility
por: Norton, Tiffany S., et al.
Publicado: (2017) -
An overview on natural farnesyltransferase inhibitors for efficient cancer therapy
por: Dai, Xiaohan, et al.
Publicado: (2020) -
Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice
por: Cuddy, Leah K., et al.
Publicado: (2022)