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Disruption of mechanical stress in extracellular matrix is related to Stanford type A aortic dissection through down-regulation of Yes-associated protein

In this study, we assessed whether the down-regulation of Yes-associated protein (YAP) is involved in the pathogenesis of extracellular matrix (ECM) mechanical stress-induced Stanford type A aortic dissection (STAAD). Human aortic samples were obtained from heart transplantation donors as normal con...

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Detalles Bibliográficos
Autores principales: Jiang, Wen-Jian, Ren, Wei-Hong, Liu, Xu-Jie, Liu, Yan, Wu, Fu-Jian, Sun, Li-Zhong, Lan, Feng, Du, Jie, Zhang, Hong-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076445/
https://www.ncbi.nlm.nih.gov/pubmed/27608489
http://dx.doi.org/10.18632/aging.101033