Age-related changes in cerebellar and hypothalamic function accompany non-microglial immune gene expression, altered synapse organization, and excitatory amino acid neurotransmission deficits

We describe age-related molecular and neuronal changes that disrupt mobility or energy balance based on brain region and genetic background. Compared to young mice, aged C57BL/6 mice exhibit marked locomotor (but not energy balance) impairments. In contrast, aged BALB mice exhibit marked energy bala...

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Detalles Bibliográficos
Autores principales: Bonasera, Stephen J., Arikkath, Jyothi, Boska, Michael D., Chaudoin, Tammy R., DeKorver, Nicholas W., Goulding, Evan H., Hoke, Traci A., Mojtahedzedah, Vahid, Reyelts, Crystal D., Sajja, Balasrinivasa, Schenk, A. Katrin, Tecott, Laurence H., Volden, Tiffany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076456/
https://www.ncbi.nlm.nih.gov/pubmed/27689748
http://dx.doi.org/10.18632/aging.101040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076456/
https://www.ncbi.nlm.nih.gov/pubmed/27689748
http://dx.doi.org/10.18632/aging.101040

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