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Global gene profiling of aging lungs in Atp8b1 mutant mice

OBJECTIVE: Recent studies implicate cardiolipin oxidation in several age-related diseases. Atp8b1 encoding Type 4 P-type ATPases is a cardiolipin transporter. Mutation in Atp8b1 gene or inflammation of the lungs impairs the capacity of Atp8b1 to clear cardiolipin from lung fluid. However, the link b...

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Detalles Bibliográficos
Autores principales: Soundararajan, Ramani, Stearns, Timothy M., Czachor, Alexander, Fukumoto, Jutaro, Turn, Christina, Westermann-Clark, Emma, Breitzig, Mason, Tan, Lee, Lockey, Richard F., King, Benjamin L., Kolliputi, Narasaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076460/
https://www.ncbi.nlm.nih.gov/pubmed/27689529
http://dx.doi.org/10.18632/aging.101056